Principal Computational Biologist - Neurology

Our client is a seed stage TechBio (£2.7m funding) building a platform solution for identifying drug targets for neurological diseases with in-vitro validation. About the role: Lead computational biology strategy for target identification in neurology, combining hands-on pipeline development with scientific leadership and cross-functional collaboration.

Key Responsibilities

• Lead QTL mapping and integrate multi-omics / functional genomics for target prioritisation
• Build and own multi-omics pipelines (QC, normalisation, analysis)
• Collaborate with ML engineers on model design, feature selection, training, evaluation, interpretation
• Define and maintain knowledge graph schemas and computational evidence layers
• Translate outputs into biological hypotheses and support in vitro validation & assay design
• Shape strategy, mentor team, and drive best practices (reproducibility, documentation) Requirements
• PhD + 5-8 years in computational biology (multi-omic target discovery)
• Strong Python, R, HPC/cloud computing
• Experience with transcriptomics, proteomics, epigenomics
• Proven work in target discovery, prioritisation, in silico validation
• Strong statistical analysis & data visualisation
• Neurology / neurodegeneration experience (preferred)
• Biotech/pharma background + strong communication & problem-solving Summary Hands-on leader driving multi-omics target discovery, integrating ML and data platforms, and working closely with experimental teams in a neurology-focused biotech.

Robert Walters Operations Limited is an employment business and employment agency and welcomes applications from all candidates