Principal Scientist - Biomarker and Translational Science - Flow Cytometry

We are working in partnership with a global pharmaceutical organisation to recruit a Senior or Principal Research Scientist with strong Flow Cytometry expertise for a newly forming Translational Research team. This opportunity sits within the company's Early Clinical Development & Translational Sciences function, working closely with an established Biomarker Assay Sciences group. The team supports the progression of innovative therapeutic assets – including gene therapies – from research through to early clinical development. This is an exciting opportunity for an experienced scientist to play a key role in shaping a new translational capability, while gaining broad exposure across the drug discovery and development pipeline in a highly collaborative environment. Responsibilities:

• Develop and deliver fit-for-purpose Flow Cytometry assays to support pre-clinical and clinical studies
• Plan, design, execute and interpret experiments, delivering high-quality, robust data
• Act as a Flow Cytometry subject matter expert, working with internal stakeholders and external CROs to share results and drive project completion
• Develop an understanding of the underlying biology and communicate this during multi-disciplinary project meetings
• Present and discuss data within multi-disciplinary project teams
• Manage workload to meet project and portfolio timelines
• Ensure compliance with Health & Safety regulations and HTA requirements Candidate profile:
• Strong hands-on expertise in Flow Cytometry assay development, validation and data analysis
• Background in immunology and experience supporting pre-clinical to clinical programmes is highly desirable
• Confident using Flow Cytometry software such as FlowJo, BD Diva, FCS Express
• Well organised, detail-focused and comfortable working independently in a fast-paced lab environment
• Confident in communicating complex scientific ideas and data to others Desirable experience:
• Broader bioanalytical techniques (e.g. LBA, LC-MS, IHC, omics, exosomes)
• Experience mentoring or managing junior scientists
• Oversight of wider bioanalytical activities within project teams The role is offered on an initial 12-month contract with realistic potential for extension and permanent opportunities. Keywords: Flow cytometry, FACS, biomarker, translational science, PK/PD, PK, PD, pharmacodynamic, pharmacokinetic, pharmaceutical, biopharmaceutical, gene therapy, immunology, research, method development, assay development, senior, principal, scientist, Slough, London, Reading, Oxford, Berkshire, Surrey, VRS9538SE